ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)

ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)

t is a cancer of White Blood Cells (WBCs), in which immature cells form lymphocytes. Normally lymphoblasts are found in the bone marrow, but in ALL lymphoblasts proliferate in large numbers in the peripheral blood. This type of cancer affects blood, bone marrow and lymph nodes, as the three are intimately connected to each other. In other words, a disease affecting one of the three will often affect the others as well.

Malignant, immature white blood cells continuously multiply and are overproduced in the bone marrow. ALL causes damage and death by crowding out normal cells in the bone marrow, and by spreading to other organs. ALL is most common in childhood with a peak incidence at 2-5 years of age and another peak in old age.
SymptomsThe ALL gets detected accidently because of the results of clinical testes conducted for some other medical issue because there are no specific symptoms for ALL in the initial stage. However, following symptoms may be an indicative of the disease-
Generalized weakness and fatigue Anemia Frequent or unexplained fever and infections Weight loss and/or loss of appetite Excessive and unexplained bruising Pain in the bone and joints (caused by the spread of “blast” cells to the surface of the bone or into the joint from the marrow cavity)Breathlessness Enlarged lymph nodes, liver and/or spleen Edema (swelling) in the lower limbs and/or abdomen Tiny red spots or lines in the skin due to low platelet levels
The signs and symptoms of ALL result from the lack of normal and healthy blood cells because they are crowded out by malignant and immature leukocytes (white blood cells). Therefore, people with ALL, experience symptoms from malfunctioning of their erythrocytes (red blood cells), leukocytes, and platelets. Laboratory tests which might show abnormalities include blood count tests, renal function tests, electrolyte tests and liver enzyme tests.
CausesThe exact causes of ALL are not known. However, the ALL could be the result of excessive generation of free radical in bone marrow or the chemical misbalance in the blood cells.

Suggestion
In the existing scenario, ALL is a controllable and manageable disease, where in a person can lead normal life with certain additional precautions.
The individual considers himself dead as soon as a person is diagnosed of cancer. The advice, behaviour and talks by relatives and friends, aggravates the situation further. Infact, this abnormal state of body needs to be understood peacefully and acted upon.

The ALL could be fatal in as less time as one week to few months if not treated in time.
Chemotherapy, Steroids, Radiotherapy, Bone Marrow Transplant (BMT) and Stem Cell Transplant (SCT) are the most prevalent treatment for ALL. All these treatments basically are very harsh and therefore it is recommended that the body must be prepared and maintained for such arduous tasks. It has been observed that the combination of above treatments along with proper nutritional support recommended below has been found extremely effective in resolving many ALL cases including the extreme serious ones.


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